I'm certainly not writing the show off... yet. :p
I still hold good hopes for the show, the voice cast is pretty A Grade, the fact that it has decent CG overall is great - I'm just nit-picking the animating/modelling of the mouth, which is really below a 14y/o par. ;)
Yes there are some minor quibbles that I have, I'm certainly not gonna judge it until I've seen it though - Animated sucked major Catalytic Converters visually but the story/writing I thought was really well done so I hope that TF:Prime at least equals this, for me. :)