Sam, I did several pages for Verno's Beast Wars online comics recently where I did digital coloring. I was getting tired of all the 3D I usually do.
Flat coloring, then tri-tone shaded, then blurs and blends, then gradient overlays, followed by textures and filters for glows and effects.
Just to emphasize; I only did the coloring, pencils/inks and text were done by others.