Lost them all?

With my comics, I'd buy the IDW classic collections of Marvel and some of the IDW runs (MTMTE). Generally easy to find still but wouldn't replace single issues.

With my toys, I would buy a couple of replacements, probably try to get some MPs (like MP10 Prime, Prowl, Sideswipe) and some of my favourites from other lines, and I would likely continue to buy new ones the same way I currently do.

I've been culling my collection over the past few years and one of the thoughts I've tried to apply is "would I replace this?" but it's generally easier though to keep things you already have. If they were all gone there's more I wouldn't replace - like most of TF:Prime toys for example if I think about it.