I say depending on the quality of the comic run.

IDW has a tendency to be inconsistent in the quality of single issues. Some issues may be very good but several are not and due to this its hard to get a clear picture on the quality of the overall story. At the end of the single issue run, you may realize that the story is not very good at all.

If you have doubts on a comic series wait till the paperback as single issues may not be worth it.