It would take me ages to compile a list considering I download and read so many each week.

But some more lesser known titles that I would recommend.

Grimm Fairy Tales (modern day re-tellings with a twist on traditional fairy tales ... and big boobs)
Hack/Slash (great little horror/slasher book)
Witchblade (absoloutely LOVE the artwork)
Un-Men (hard to describe, just check it out)
Tarot - Witch of the Black Rose (mature readers only. Stories are so so, artwork is great, mostly because of the nudity )
Iron and the Maiden (it was a mini-series that featured some amazing art deco inspired art work and a great story to boot.)

Currently enjoying Secret Invasion, though this month seems to be stalling. But no where near as stalled as Final Crisis. That's a story that needs to seriously pick it's game or it will be overshadowed by Batman R.I.P.

And i'd have to say my pick of DC Comics would be Green Lantern Corps. Can't wait for the blackest night storyline that's coming up.

Marvel wise, absoloutely loving Nova and Guardians of the Galaxy (speaking of which, Annihilation and Annihilation:Conquest, great reads) and can't wait for SI to hit those books.