Not really. As was pointed out earlier, rare vintage G1 MISB items would become (and are becoming) extinct if it weren't for the few dedicated MISB collectors who are preserving these items, for us and for future generations. Opening and playing with toys is perfectly fine, but rather than destroy what little there is left of vintage MISB stuff, why not just open and play with reissues instead? Or better yet, find some that are already loose.
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