Although I'm not familiar with the franchise, given the height difference between a pony (not even a horse, but a freaking pony) and even the weakest frailest of Decepticons, I'm thinking it will be a short battle involving disarticulation and gore. So I'm not entirely sure how you could write a comic about it, but kind of curious to see what mayhem will be involved.

I can imagine Starscream and the seekers chasing after flying ponies though! Who knows, maybe Starscream could even make a new friend, like Thundercracker with his dog