I think you've hit the nail on the head there for me.

Nightshade's gender-neutral pronouns stand out more to me because the show takes the time to explicitly point it out instead of just using it naturally and allowing the audience to notice it organically. I would prefer the latter because that's how it works in real life. Every transgender and gender neutral person that I know doesn't go around telling people what their preferred pronouns are. We just know and recognise it as we would for anyone else. It just happens.