For me it's PS3 all the way. The only problems I've encounterred with it is:
It sometimes crashes, usually while playing Fallout 3.
No television reception when it's turned on
The fuse box to my apartment complex caught fire the first time I turned it on.

Other then that no problems.
I've played the Xbox and it just isn't for me, not sure why and the Wii just isn't my thing either though there are quite a few games I would like for it.

PS3 also plays Blu-ray so I don't have to get one